Ever since its discovery by Windhaus, the importance of the active metabolite of vitamin D (1,25-dihydroxyvitamin D3; 1,25-(OH)2D3) has been ever expanding. In this review, the attention is shifted towards the importance of the extra-skeletal effects of vitamin D, with special emphasis on the immune system. The first hint of the significant role of vitamin D on the immune system was made by the discovery of the presence of the vitamin D receptor on almost all cells of the immune system. In vitro, the overwhelming effect of supra-physiological doses of vitamin D on the individual components of the immune system is very clear. Despite these promising pre-clinical results, the translation of the in vitro observations to solid clinical effects has mostly failed. Nevertheless, the evidence of a link between vitamin D deficiency and adverse outcomes is overwhelming and clearly points towards avoidance of vitamin D deficiency especially in early life.
Read full text: Martens P-J, Gysemans C, Verstuyf A, Mathieu C. Vitamin D’s Effect on Immune Function. Nutrients. 2020; 12(5):1248.
Vitamin D’s Effect on Immune Function https://t.co/mkipwN5aXt #INPST #VitaminD #ImmuneFunction @erlesen @HealthyFellow @JJ_Angelus @MarcoAlbuja @ShraboniGhosal @VicenteLozadaB @nathantwala @PepperPell @deNutrients @grawoig— INPST (@_INPST) August 22, 2020
Other social media channels: https://t.co/WO0pc6I3Q9 pic.twitter.com/YQasrJhZmz
Why publish with Current Research in Biotechnology? Quality. Speed. Visibility. https://t.co/xj0ri5DgNI #CRBIOTECH #INPST pic.twitter.com/jcIVOavjjf— Atanas G. Atanasov (@_atanas_) June 26, 2019
The International Natural Product Sciences Taskforce (INPST) maintains up-to-date lists with conferences, grants and funding opportunities, jobs and open positions, and journal special issues with relevance for the area of phytochemistry and food chemistry, pharmacology, biotechnology, medicine and pharmacognosy research, and natural product science.
Join for free INPST as a member