Natural molecule derivatives as Topoisomerase Poisons – Insights into chemotherapeutic failure

By Syed Moiz Ahmed

Contribution participating in the INPST 2018 Science Communication Awards contest.

With the rapid increase in our understanding of disease biology, it is quite evident that treatment outcomes are dependent on patient molecular profiles. The focus is now to get the right treatment to the right patient allowing for greater safety and efficacy. The authors have shed light on a molecular biomarker that could potentially be used in this new treatment paradigm. 

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