Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), with a clinical outcome ranging from mild to severe, including death. To date, it is unclear why some patients develop severe symptoms. Many authors have suggested the involvement of vitamin D in reducing the risk of infections; thus, we retrospectively investigated the 25-hydroxyvitamin D (25(OH)D) concentrations in plasma obtained from a cohort of patients from Switzerland. In this cohort, significantly lower 25(OH)D levels (p = 0.004) were found in PCR-positive for SARS-CoV-2 (median value 11.1 ng/mL) patients compared with negative patients (24.6 ng/mL); this was also confirmed by stratifying patients according to age >70 years. On the basis of this preliminary observation, vitamin D supplementation might be a useful measure to reduce the risk of infection. Randomized controlled trials and large population studies should be conducted to evaluate these recommendations and to confirm our preliminary observation.
25-Hydroxyvitamin D Concentrations Are Lower in Patients with Positive PCR for SARS-CoV-2 https://t.co/O5j7BuVsOb #VitaminD #SARSCoV2 #Vitamins @erlesen @HealthyFellow @PepperPell @ShraboniGhosal @MarcoAlbuja @nathantwala
— INPST (@_INPST) May 24, 2020
Other social media channels: https://t.co/WO0pc6I3Q9 pic.twitter.com/e28YsePHfi
Why publish with Current Research in Biotechnology? Quality. Speed. Visibility. https://t.co/xj0ri5DgNI #CRBIOTECH #INPST pic.twitter.com/jcIVOavjjf
— Atanas G. Atanasov (@_atanas_) June 26, 2019
The International Natural Product Sciences Taskforce (INPST) maintains up-to-date lists with conferences, grants and funding opportunities, jobs and open positions, and journal special issues with relevance for the area of phytochemistry and food chemistry, pharmacology, biotechnology, medicine and pharmacognosy research, and natural product science.
Join for free INPST as a member