NTZ Lab Ltd. has just published the discovery of new multi-target compounds; check out our new article in European Journal of Medicinal Chemistry

In this new work, a comprehensive study is performed for the first time to compare a series of promising anti-Parkinson´s and anti-Alzeheimer´s disease derivatives.

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Reference:

Nikolay T. Tzvetkov, Hans-Georg Stammler, Maya G. Georgieva, Daniela Russo, Immacolata Faraone, Aneliya A. Balacheva, Silvia Hristova, Atanas G. Atanasov, Luigi Milella, Liudmil Antonov, Marcus Gastreich. Carboxamides vs. methanimines: Crystal structures, binding interactions, photophysical studies, and biological evaluation of (indazole-5-yl)methanimines as monoamine oxidase B and acetylcholinesterase inhibitors. European Journal of Medicinal Chemistry, Volume 179, 2019, Pages 404-422. https://doi.org/10.1016/j.ejmech.2019.06.041



Keywords: Alzeheimer´s disease, Parkinson’s disease, Neuroprotection, NTZ Lab.

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