Volatiles from the hypoxylaceous fungi Hypoxylon griseobrunneum and Hypoxylon macrocarpum

Abstract:

The volatiles emitted by the ascomycetes Hypoxylon griseobrunneum and Hypoxylon macrocarpum (Hypoxylaceae, Xylariales) were collected by use of a closed-loop stripping apparatus (CLSA) and analysed by GC–MS. The main compound class of both species were polysubstituted benzene derivatives. Their structures could only be unambiguously determined by comparison to all isomers with different substitution patterns. The substitution pattern of the main compound from H. griseobrunneum, the new natural product 2,4,5-trimethylanisole, was explainable by a polyketide biosynthesis mechanism that was supported by a feeding experiment with (methyl-2H3)methionine.

Read full text

Reference:

Rinkel J, Babczyk A, Wang T, Stadler M, Dickschat JS. Volatiles from the hypoxylaceous fungi Hypoxylon griseobrunneum and Hypoxylon macrocarpum. Beilstein J Org Chem. 2018 Dec 4;14:2974-2990. doi: 10.3762/bjoc.14.277. eCollection 2018. PubMed PMID: 30591821; PubMed Central PMCID: PMC6296411.

Volatiles from the hypoxylaceous fungi Hypoxylon griseobrunneum and Hypoxylon macrocarpum
Volatiles from the hypoxylaceous fungi Hypoxylon griseobrunneum and Hypoxylon macrocarpum

Keywords: volatiles from Hypoxylon griseobrunneum and Hypoxylon macrocarpum, hypoxylaceous fungi, polyketide biosynthesis, 2,4,5-trimethylanisole, ascomycetes.


Join for free INPST as a member

The International Natural Product Sciences Taskforce (INPST) maintains up-to-date lists with conferences, grants and funding opportunities, jobs and open positions, and journal special issues with relevance for the area of phytochemistry and food chemistry, pharmacology, pharmacognosy research, and natural product science.

Leave a Reply

avatar
  Subscribe  
Notify of